Shivali Kohli, PhD student in the School of Life Sciences at The University of Nottingham

School of Life Sciences

University of Nottingham

Project: Evaluating the use of GlyT1 inhibitors for the negative symptoms of schizophrenia in a preclinical model.

Q: Why did you choose to study at Nottingham?

A: The project on offer was exactly the type of PhD I was searching for, and funding for the project was already in place so did not require further applications from another funding source.

Perhaps more importantly, my principal supervisor had the relevant experience to supervise a PhD student, as well as being established in the field of translational neuroscience.

Q: What’s the aim of your PhD research?

A: Negative symptoms of Schizophrenia remain poorly treated by current antipsychotic medication. One of the new approaches to improve these symptoms is to co-administer GlyT1 inhibitors, a type of drug.

My project aimed to evaluate the use of these drugs in improving negative symptoms in schizophrenia, and determine the changes that occurred in the brain following single or repeated administration.

Q: What do you enjoy most about your PhD?

A: The most enjoyable part is getting a chance to plan your own experiments and develop as an independent researcher. It is also pretty cool to know that even if the overall impact of your project seems small in the grand scheme of things, it is helping to increase knowledge and awareness in the field.

Q: What’s it like living in Nottingham?

A: I’ve really enjoyed living in Nottingham, partly because the campus is beautiful. Additionally, there’s always something on and something to do – Nottingham is quite a cultural place and there are often community-wide events on at Lakeside Arts theatre on campus, or in the town centre, so there’s plenty to get involved in.

Q: What advice would you give to other students looking to study a PhD at Nottingham?

A: There’s a lot of support and advice available for postgraduate students at Nottingham – whether it concerns settling into your project, problems during your PhD, or finding employment afterwards. My advice would be to use these facilities as they really do help.

Also, take time to get involved in postgraduate events throughout the year (there are quite a few) as it is a good way to meet other students, and take a break from academic work with like-minded people.

Find out more about postgraduate opportunities at Nottingham at: www.nottingham.ac.uk/pgstudy

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